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KMID : 1059519940380100763
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Journal of the Korean Chemical Society
1994 Volume.38 No. 10 p.763 ~ p.768
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Synthesis of Dolastatin 10 Analogues
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Kim In-Kyu
Lee Byoung-Suk
Hong Young-Tech
Choi Ha-Soon
Kwon Nam-Yoen
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Abstract
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As a part of synthetic programs aimed at Dolastatin 10 analogues, synthetic pathway toward various peptides were investigated. 4-Amino-3-hydr> Transfer interrupted!nalogues were prepared by ring opening of epoxides with ammonia in MeOH. Several peptides were prepared starting from these unusual amino acids through using mainly DCC coupling.
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